Cyp33 is an essential human cyclophilin prolyl isomerase that plays myriad roles in splicing and chromatin remodeling.In addition to a canonical cyclophilin (Cyp) domain, Cyp33 contains an RNA-recognition motif (RRM) domain, and RNA-binding triggers proline isomerase activity.One prominent role for Cyp33 is through a direct interaction with the mix

The quest to develop high-performance metallic alloys with properties superior to traditional alloys has driven scientists to synthesize numerous chemical alloy compositions over the past few decades.However, many of these compositions heavily depend on strategic and critical raw materials (S&CRMs), leading to significant environmental impacts due

Hydraulic fracturing technique increases shale gas well productivity significantly.Horizontal well fracture optimization has been studied by many researchers worldwide in the past decade.However, most of these researches relied on computationally expensive numerical simulation models for objectives evaluation during the optimization process.This af

Currently there is considerable interest in the legislative debate around generic biological drugs or "biosimilars" in the EU and US due to the large, lucrative market that it offers to the industry.While some countries have issued a few regulatory guidelines as well as product specific requirements, there is no general consensus as to a single, si

Category: Ankle; Arthroscopy; Trauma Introduction/Purpose: Ankle fractures are among the most common operatively treated injuries by orthopedic surgeons.However, up to 20% of patients will have continued pain and poor patient reported outcomes despite good/excellent radiographic results.Ankle fractures typically occur with varying degrees of intra-